In the a good airplane pilot study, Sullivan and acquaintances (2013) evaluated the usage of endoscopic ambition therapy for the treatment of obesity

AspireAssist Ambition Treatment

This method entails endoscopic placement of a gastrostomy tube (A-Tube) and the AspireAssist siphon assembly (Aspire Bariatrics, King of Prussia, PA) to aspirate gastric contents 20 minutes after meal consumption. These researchers performed a study of 18 obese subjects who were randomly assigned (2:1) to groups that underwent aspiration therapy for 1 year plus lifestyle therapy (n = 11; mean BMI, 42.6 ± 1.4 kg/m(2)) or lifestyle therapy only (n = 7; mean BMI, 43.4 ± 2.0 kg/m(2)). Lifestyle intervention comprised a 15-session diet and behavioral education program; 10 of the 11 subjects who underwent aspiration therapy and 4 of the 7 subjects who underwent lifestyle therapy completed the 1st year of the study. After 1 year, subjects in the aspiration therapy group lost 18.6 % ± 2.3 % of their body weight (49.0 % ± 7.7 % of EWL) and those in the lifestyle therapy group lost 5.9 % ± 5.0 % (14.9 % ± 12.2 % of EWL) (p < 0.04); 7 of the 10 subjects in the aspiration therapy group completed an additional year of therapy and maintained a 20.1 % ± 3.5 % body weight loss (54.6 % ± 12.0 % of EWL). There were no AEs of aspiration therapy on eating behavior and no evidence of compensation for aspirated calories with increased food intake. No episodes of binge eating in the aspiration therapy group or serious AEs were reported. The authors concluded that aspiration therapy appeared to be a safe and effective long-term weight loss therapy for obesity. These preliminary findings from a pilot study need to be validated by well-designed studies.

Forssell and you can Noren (2015) evaluated the potency of a novel tool, brand new AspireAssist ambition therapy system, for treating carrying excess fat. Shortly after four weeks delivering a highly-low-energy diet plan, 25 heavy individuals (Body mass index 39.8 ± 0.nine kg/m(2)) met with the AspireAssist gastrostomy tube put swipe during the a beneficial gastroscopy. A decreased-reputation device was strung 2 weeks later on and you can ambition regarding gastric material was performed approximately 20 minutes or so immediately after snacks three times per go out. Cognitive behavioral cures was also come. In the month 6, mean pounds missing is actually sixteen.5 ± 7.8 kg in the 22 subjects who completed twenty six days out-of medication (p = 0.001). The fresh imply percentage EWL was forty.8 ± 19.8 % (p = 0.001); dos victims was indeed hospitalized to own difficulties: 1 subject for soreness after gastrostomy tube location, which was addressed with analgesics, plus one on account of an aseptic intra-intestinal liquid collection a day once gastrostomy tubing position. No medically high changes in serum potassium and other electrolytes happened. This new article writers figured contained in this data, good-sized weightloss is hit that have couples issue utilising the AspireAssist program, indicating its possible because the an appealing healing unit to own obese customers.

Successful aspiration necessary thorough chewing away from ingested eating

In a prospective observational study, Noren and Forssell (2016) evaluated the safety and effectiveness of the novel AspireAssist Aspiration Therapy System for treatment of obesity, and its effect on patient’s quality of life. A total of 25 obese subjects, mean age of 48 years (range of 33 to 65) were included in this study. A custom gastrostomy tube (A-tube) was percutaneously inserted during a gastroscopy performed under conscious sedation. Drainage and irrigation of the stomach were performed 3 times daily, 20 mins after each meal, for 1 to 2 years. Treatment included a cognitive behavioral weight loss program. Mean BMI at inclusion was 39.8 kg/m2 (range of 35 to 49). After 1 year mean (SD) BMI was 32.1 kg/m2 (5.4), p < 0.01, and EWL was 54.4 % (28.8), p < 0.01. Quality of life, as measured with EQ-5D, improved from 0.73 (0.27) to 0.88 (0.13), p < 0.01. After 2 years BMI was 31.0 kg/m2 (5.1), p < 0.01, and EWL was 61.5 % (28.5), p < 0.01. There were no serious AEs or electrolyte disorderspliance was 80 % after 1 year and 60 % after 2 years. The authors concluded that aspiration therapy is a safe and efficient treatment for obesity, and weight reduction improves quality of life. Excess weight was approximately halved in a year, with weight stability if treatment was continued; and long-term results remain to be investigated.